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Anti-SLC47A1 Polyclonal Antibody

Catalog No. TMAB-12906 Copy Product Info
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Anti-SLC47A1 Polyclonal Antibody is a Rabbit antibody targeting SLC47A1. Anti-SLC47A1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-SLC47A1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-12906

Anti-SLC47A1 Polyclonal Antibody is a Rabbit antibody targeting SLC47A1. Anti-SLC47A1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-SLC47A1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SLC47A1 Polyclonal Antibody is a Rabbit antibody targeting SLC47A1. Anti-SLC47A1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Cow,Horse,Rabbit,Sheep)
Verified Activity
1. Sample:
293T Cell (Human) Lysate at 40 μg
Adrenal gand (Mouse) Lysate at 40 μg
Primary: Anti-SLC47A1 (TMAB-12906) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 58 kD
Observed band size: 62 kD
2. Paraformaldehyde-fixed, paraffin embedded (rat liver tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (SLC47A1) Polyclonal Antibody, Unconjugated (TMAB-12906) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane. Predominantly localized at the plasma membrane but also found in intracellular organelles.
Tissue SpecificityExpressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membranes of the urinary tubules, bile caniculi and brush border membranes).
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SLC47A1
Antigen Species
Human
Gene Name
SLC47A1
Gene ID
Protein Name
Multidrug and toxin extrusion protein 1
Uniprot ID
Function
Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.
Chemical Properties
Molecular WeightTheoretical: 58 kDa. Actual: 62 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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