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Anti-CD46 Polyclonal Antibody

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Catalog No. TMAB-04007

Anti-CD46 Polyclonal Antibody is a Rabbit antibody targeting CD46. Anti-CD46 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,FCM.

Anti-CD46 Polyclonal Antibody

Anti-CD46 Polyclonal Antibody

😃Good
Catalog No. TMAB-04007
Anti-CD46 Polyclonal Antibody is a Rabbit antibody targeting CD46. Anti-CD46 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CD46 Polyclonal Antibody is a Rabbit antibody targeting CD46. Anti-CD46 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
Reactivity
Human,Mouse
Application
WB
IHC-P
IHC-Fr
IF
FCM
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationIsoform 1: Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein. Note=Inner acrosomal membrane of spermatozoa. Isoform 2: Secreted (Probable).
Tissue SpecificityPresent only in testis (at protein level).
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCD46 is one of the membrane complement regulatory proteins. CD46 possesses C3b-binding and factor I cofactor activities which play important roles in the regulation of the complement activation pathway. CD46 is widely distributed on blood cells, endothelial cells, epithelial cells and tumor cell lines. CD46 exists as many isoforms in a variety of tissues. The antigen has a broad distribution and is present on leukocytes, platelets, endothelial cells, epithelial cells and fibroblasts. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. It is expressed on thymocytes, B cells, monocytes, granulocytes, NK cells, platelets, epithelial and endothelial cells.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CD46
Antigen Species
Human
Gene Name
CD46
Gene ID
4179
Protein Name
Membrane cofactor protein
Uniprot ID
P15529
Function
May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
Chemical Properties
Molecular WeightTheoretical: 43 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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