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Anti-MGLUR5 Polyclonal Antibody
Catalog No. TMAB-08795 Copy Product Info
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Anti-MGLUR5 Polyclonal Antibody is a Rabbit antibody targeting MGLUR5. Anti-MGLUR5 Polyclonal Antibody can be used in WB.
Anti-MGLUR5 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-08795
Anti-MGLUR5 Polyclonal Antibody is a Rabbit antibody targeting MGLUR5. Anti-MGLUR5 Polyclonal Antibody can be used in WB.
Anti-MGLUR5 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-MGLUR5 Polyclonal Antibody is a Rabbit antibody targeting MGLUR5. Anti-MGLUR5 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Cow,Horse,Sheep,Monkey) |
| Verified Activity | 1. Sample: Cerebral cortex (Mouse) Lysate at 40 μg Hippocampus (Mouse) Lysate at 40 μg Primary: Anti-MGLUR5 (TMAB-08795) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 130 kD Observed band size: 130 kD 2. Sample: Cerebrum (Mouse) Lysate at 40 μg Primary: Anti-MGLUR5 (TMAB-08795) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 130 kD Observed band size: 130 kD 3. Sample: Lane 1: Cerebrum (Mouse) Lysate at 40 μg Lane 2: Cerebrum (Rat) Lysate at 40 μg Primary: Anti-MGLUR5 (TMAB-08795) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: >140 kD Observed band size: 160 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell Membrane |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors (mGluRs). Metabotropic Glutamate Receptor 5b (GRM5) activity is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The metabotropic glutamate receptor type 5 (mGlu5) is expressed in two splice variants, mGlu5a and mGlu5b, which differ in that mGlu5b has a 33-amino acid insert in the intracellular C-terminal domain. This receptor subtype is highly regulated, with higher levels found in developing animals. |
| Immunogen | KLH conjugated synthetic peptide: human MGLUR5 |
| Antigen Species | Human |
| Gene Name | GRM5 |
| Gene ID | |
| Protein Name | Metabotropic glutamate receptor 5 |
| Uniprot ID | |
| Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteKns) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity. |
| Molecular Weight | Theoretical: 130 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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