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Anti-DULLARD Polyclonal Antibody

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Catalog No. TMAB-05334

Anti-DULLARD Polyclonal Antibody is a Rabbit antibody targeting DULLARD. Anti-DULLARD Polyclonal Antibody can be used in WB.

Anti-DULLARD Polyclonal Antibody

Anti-DULLARD Polyclonal Antibody

😃Good
Catalog No. TMAB-05334
Anti-DULLARD Polyclonal Antibody is a Rabbit antibody targeting DULLARD. Anti-DULLARD Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-DULLARD Polyclonal Antibody is a Rabbit antibody targeting DULLARD. Anti-DULLARD Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Cow,Horse)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane; Single-pass membrane protein. Nuclear membrane; Single-pass membrane protein.
Tissue SpecificityMuscle specific with lower expression in other metabolic tissues.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundIn eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. Dullard, also known as NET56, is a 244 amino acid single-pass membrane protein that localizes to both the nucleus and the endoplasmic reticulum and contains one FCP1 homology domain. Functioning as a serine/threonine phosphatase, Dullard catalyses the dephosphorylation of target proteins and is thought to be required for proper nuclear membrane morphology. Human Dullard shares 92% sequence identity with its zebrafish counterpart, suggesting a conserved role between species.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human DULLARD
Antigen Species
Human
Gene Name
CTDNEP1
Gene ID
23399
Protein Name
CTD nuclear envelope phosphatase 1
Uniprot ID
O95476
Function
DULLARD is a serine/threonine phosphatase which may be required for proper nuclear membrane morphology. It is involved in LPIN1 dephosphorylation and may antagonize BMP signaling.
Chemical Properties
Molecular WeightTheoretical: 28 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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