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Anti-MECR Polyclonal Antibody
😃Good
Catalog No. TMAB-08703
Anti-MECR Polyclonal Antibody is a Rabbit antibody targeting MECR. Anti-MECR Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-MECR Polyclonal Antibody
Anti-MECR Polyclonal Antibody
😃Good
Catalog No. TMAB-08703
Anti-MECR Polyclonal Antibody is a Rabbit antibody targeting MECR. Anti-MECR Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-MECR Polyclonal Antibody is a Rabbit antibody targeting MECR. Anti-MECR Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Rabbit,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion. |
| Tissue Specificity | Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Mecr is a 373 amino acid mitochondrial protein that may play a role in fatty acid synthesis. Existing as two alternatively spliced isoforms, Mecr is highly expressed in cardiac and skeletal muscle, with lower levels found in pancreas, kidney, placenta and liver. Mecr forms a homodimer and belongs to the zinc-containing alcohol dehydrogenase family and quinone oxidoreductase subfamily. Mecr reduces trans-2-enoyl-CoA to acyl-CoA in an NADPH-dependent manner and is encoded by a gene that maps to human chromosome 1p35.3. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. |
| Immunogen | KLH conjugated synthetic peptide: human MECR |
| Antigen Species | Human |
| Gene Name | MECR |
| Gene ID | |
| Protein Name | Enoyl-[acyl-carrier-protein] reductase, mitochondrial |
| Uniprot ID | |
| Function | Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids. |
| Molecular Weight | Theoretical: 36 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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