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Anti-MYST1/KAT8 Polyclonal Antibody 2
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Catalog No. TMAB-09193
Anti-MYST1/KAT8 Polyclonal Antibody 2 is a Rabbit antibody targeting MYST1/KAT8. Anti-MYST1/KAT8 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Anti-MYST1/KAT8 Polyclonal Antibody 2
Anti-MYST1/KAT8 Polyclonal Antibody 2
Copy Product Info😃Good
Catalog No. TMAB-09193
Anti-MYST1/KAT8 Polyclonal Antibody 2 is a Rabbit antibody targeting MYST1/KAT8. Anti-MYST1/KAT8 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-MYST1/KAT8 Polyclonal Antibody 2 is a Rabbit antibody targeting MYST1/KAT8. Anti-MYST1/KAT8 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Pig,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | 1. Protein: testis (mouse) lysate at 40 μg; Primary: rabbit Anti-MYST1/KAT8 (TMAB-09193) at 1:300; Secondary: HRP conjugated Goat-Anti-rabbit IgG at 1: 5000; Predicted band size: 52 kD Observed band size: 55 kD 2. Paraformaldehyde-fixed, paraffin embedded (Mouse kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (MYST1/KAT8) Polyclonal Antibody, Unconjugated (TMAB-09193) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 3. Sample: Testis (Rat) Lysate at 40 μg Primary: Anti-KAT8 (TMAB-09193) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 52 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Chromosome. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Dosage compensation ensures that males with a single X chromosome and females with two X chromosomes have the same amount of most X-linked gene products. In Drosophila, this is acheived by enhancing the level of transcription of the X chromosome in males. Proteins such as maleless, male specific lethal 1, 2 and 3, and males absent on the first (MOF) form a dosage compensation complex (DCC) that is required for the twofold increase of transcription of the male X chromosome. The DCC is preferentially associated with many sites on the X chromosome in somatic cells of males. The binding of the DCC to the X chromosome is dependent upon histone 4 acetylation at lysine 16, which is accomplished by MOF. In mammals, MOF (also designated hMOF, MYST1, or MOZ) belongs to the MYST family of histone acetyl transferases which are characterized by a unique C2HC-type zinc finger close to their HAT domains. MOF utilizes the zinc finger domain to contact the globular part of the nucleosome as well as the histone H4 N-terminal tail substrate. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone acetyltransferases. |
| Immunogen | KLH conjugated synthetic peptide: human MOF/KAT8/MYST1 |
| Antigen Species | Human |
| Gene Name | KAT8 |
| Gene ID | |
| Protein Name | Histone acetyltransferase KAT8 |
| Uniprot ID | |
| Function | Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. |
| Molecular Weight | Theoretical: 52 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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