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Anti-Phospho-FRS2 (Tyr436) Polyclonal Antibody 2

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Catalog No. TMAB-10720

Anti-Phospho-FRS2 (Tyr436) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-FRS2 (Tyr436). Anti-Phospho-FRS2 (Tyr436) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.

Anti-Phospho-FRS2 (Tyr436) Polyclonal Antibody 2

Anti-Phospho-FRS2 (Tyr436) Polyclonal Antibody 2

😃Good
Catalog No. TMAB-10720
Anti-Phospho-FRS2 (Tyr436) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-FRS2 (Tyr436). Anti-Phospho-FRS2 (Tyr436) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-FRS2 (Tyr436) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-FRS2 (Tyr436). Anti-Phospho-FRS2 (Tyr436) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Rabbit)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndomembrane system. Note=Cytoplasmic, membrane-bound.
Tissue SpecificityHighly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundAdapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. Tissue specificity:Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.
Antigen Details
Immunogen
KLH conjugated synthesised phosphopeptide: human FRS2 around the phosphorylation site of Tyr436
Antigen Species
Human
Gene Name
FRS2
Gene ID
Protein Name
Fibroblast growth factor receptor substrate 2
Uniprot ID
Function
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
Chemical Properties
Molecular WeightTheoretical: 57 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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