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Anti-CRLS1 Polyclonal Antibody

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Catalog No. TMAB-04684

Anti-CRLS1 Polyclonal Antibody is a Rabbit antibody targeting CRLS1. Anti-CRLS1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-CRLS1 Polyclonal Antibody

Anti-CRLS1 Polyclonal Antibody

😃Good
Catalog No. TMAB-04684
Anti-CRLS1 Polyclonal Antibody is a Rabbit antibody targeting CRLS1. Anti-CRLS1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CRLS1 Polyclonal Antibody is a Rabbit antibody targeting CRLS1. Anti-CRLS1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Chicken,Dog,Pig,Cow,Horse)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion inner membrane.
Tissue SpecificityHighly expressed in tissues such as heart, skeletal muscle and liver.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCardiolipin synthetase is a mitochondrial protein that belongs to the CDP-alcohol phosphatidyltransferase class-I family. CLS1 is a multi-pass membrane protein localized to the inner membrane of mitochondria. CLS1 is responsible for the catalyzing the reversible transfer of a phosphatidyl group from one phosphatidyl glycerol molecule to another. This process results in the formation of cardiolipin (CL, or diphosphatidyl glycerol) and glycerol. Diphosphatidyl glycerol is a major component of the mitochondrial membrane and constitutes roughly 20% of total mitochondrial lipids. Having four fatty acid tails rather than the usual two, CL is a double phospholipid that is synthesized in the mitochondrion itself. Defects in the CRLS1 gene are likely to effect metabolism, sustained production of ATP and could contribute to diseases such as Barth syndrome.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CRLS1
Antigen Species
Human
Gene Name
CRLS1
Gene ID
54675
Protein Name
Cardiolipin synthase(CMP-forming)
Uniprot ID
Q9UJA2
Function
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
Chemical Properties
Molecular WeightTheoretical: 33 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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