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Anti-ANT-1 Polyclonal Antibody

Catalog No. TMAB-02604 Copy Product Info
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Anti-ANT-1 Polyclonal Antibody is a Rabbit antibody targeting ANT-1. Anti-ANT-1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-ANT-1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-02604

Anti-ANT-1 Polyclonal Antibody is a Rabbit antibody targeting ANT-1. Anti-ANT-1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-ANT-1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ANT-1 Polyclonal Antibody is a Rabbit antibody targeting ANT-1. Anti-ANT-1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep)
Verified Activity
Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min;
Incubation: Anti-ANT-1 Polyclonal Antibody, Unconjugated (TMAB-02604) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion inner membrane; Multi-pass membrane protein.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundDefects in SLC25A4 are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions autosomal dominant type 2 (PEOA2) [MIM:609283]. Progressive external ophthalmoplegia is characterized by progressive weakness of ocular muscles and levator muscle of the upper eyelid. In a minority of cases, it is associated with skeletal myopathy, which predominantly involves axial or proximal muscles and which causes abnormal fatigability and even permanent muscle weakness. Ragged-red fibers and atrophy are found on muscle biopsy. A large proportion of chronic ophthalmoplegias are associated with other symptoms, leading to a multisystemic pattern of this disease. Additional symptoms are variable, and may include cataracts, hearing loss, sensory axonal neuropathy, ataxia, depression, hypogonadism, and parkinsonism.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ANT-1
Antigen Species
Human
Gene Name
SLC25A4
Gene ID
291
Protein Name
ADP/ATP translocase 1
Uniprot ID
P12235
Function
Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
Chemical Properties
Molecular WeightTheoretical: 33 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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