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Anti-CD174/FUT3 Polyclonal Antibody
😃Good
Catalog No. TMAB-03882
Anti-CD174/FUT3 Polyclonal Antibody is a Rabbit antibody targeting CD174/FUT3. Anti-CD174/FUT3 Polyclonal Antibody can be used in WB.
Anti-CD174/FUT3 Polyclonal Antibody
Anti-CD174/FUT3 Polyclonal Antibody
😃Good
Catalog No. TMAB-03882
Anti-CD174/FUT3 Polyclonal Antibody is a Rabbit antibody targeting CD174/FUT3. Anti-CD174/FUT3 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CD174/FUT3 Polyclonal Antibody is a Rabbit antibody targeting CD174/FUT3. Anti-CD174/FUT3 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Plasma membrane - adsorbed onto the surface of erythrocytes. |
| Tissue Specificity | Highly expressed in stomach, colon, smallintestine, lung and kidney and to a lesser extent in salivarygland, bladder, uterus and liver. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, which are reliant on adhesion molecules such as Selectins (1-3). Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6). Blood Group Lewis b is a carbohydrate determinant carried on both glycolipids and glycoproteins. |
| Immunogen | KLH conjugated synthetic peptide: human FUT3 |
| Antigen Species | Human |
| Gene Name | FUT3 |
| Gene ID | |
| Protein Name | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 |
| Uniprot ID | |
| Function | Blood group Lewis b is a carbohydrate determinant carried on both glycolipids and glycoproteins, detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. |
| Molecular Weight | Theoretical: 42 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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