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Anti-SAKS1/2B28 Polyclonal Antibody

Catalog No. TMAB-12479 Copy Product Info
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Anti-SAKS1/2B28 Polyclonal Antibody is a Rabbit antibody targeting SAKS1/2B28. Anti-SAKS1/2B28 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-SAKS1/2B28 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-12479

Anti-SAKS1/2B28 Polyclonal Antibody is a Rabbit antibody targeting SAKS1/2B28. Anti-SAKS1/2B28 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-SAKS1/2B28 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SAKS1/2B28 Polyclonal Antibody is a Rabbit antibody targeting SAKS1/2B28. Anti-SAKS1/2B28 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Pig,Cow,Horse,Sheep)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (rat uterus); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (SAKS1 2B28) Polyclonal Antibody, Unconjugated (TMAB-12479) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research Background2B28 is a component of a complex composed of NGLY1, SAKS1, AMFR, VCP and RAD23B, where it acts as an adapter that directs VCP to polyubiquitinated proteins. 2B28 also interacts with Homer 2, which further suggests role for 2B28 in the regulation of protein degradation by ubiquitin-proteasome systems.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SAKS1/2B28
Antigen Species
Human
Gene Name
UBXN1
Gene ID
Protein Name
UBX domain-containing protein 1
Uniprot ID
Function
Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol. Involved in ubiquitin-proteasome systems. 2 named isoforms exist.
Chemical Properties
Molecular WeightTheoretical: 33 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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