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Anti-DBC2 Polyclonal Antibody
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Catalog No. TMAB-04992
Anti-DBC2 Polyclonal Antibody is a Rabbit antibody targeting DBC2. Anti-DBC2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-DBC2 Polyclonal Antibody
Anti-DBC2 Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-04992
Anti-DBC2 Polyclonal Antibody is a Rabbit antibody targeting DBC2. Anti-DBC2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-DBC2 Polyclonal Antibody is a Rabbit antibody targeting DBC2. Anti-DBC2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Pig,Cow,Horse) |
| Verified Activity | Tissue/cell: human breast carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-DBC2 Polyclonal Antibody, Unconjugated (TMAB-04992) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Tissue Specificity | Ubiquitous, with highest levels in neural tissues. Expression is also detected in fetal lung, heart, and brain. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | DBC2 is a member of the recently identified RhoBTB family, which is part of the Rho GTPase family. DBC2 has been implicated as a tumor suppressor in breast and lung cancer. Studies have shown that DBC2 binds to the ubiquitin ligase scaffold Cul3, and that Cul3 regulates DBC2 protein levels by ubiquitinating DBC2 directly, leading to its degradation by the proteasome. |
| Immunogen | KLH conjugated synthetic peptide: human DBC2 |
| Antigen Species | Human |
| Gene Name | RHOBTB2 |
| Gene ID | |
| Protein Name | Rho-related BTB domain-containing protein 2 |
| Uniprot ID |
| Molecular Weight | Theoretical: 83 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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