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Anti-CELF3 Polyclonal Antibody
Catalog No. TMAB-04217 Copy Product Info
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Anti-CELF3 Polyclonal Antibody is a Rabbit antibody targeting CELF3. Anti-CELF3 Polyclonal Antibody can be used in WB.
Anti-CELF3 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-04217
Anti-CELF3 Polyclonal Antibody is a Rabbit antibody targeting CELF3. Anti-CELF3 Polyclonal Antibody can be used in WB.
Anti-CELF3 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CELF3 Polyclonal Antibody is a Rabbit antibody targeting CELF3. Anti-CELF3 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Pig,Cow) |
| Verified Activity | 1. Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Cerebellum tissue lysates Lane 3: Rat Cerebrum tissue lysates Lane 4: Rat Cerebellum tissue lysates Lane 5: Human SH-SY5Y cell lysates Primary: Anti-CELF3 (TMAB-04217) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 42-55 kD 2. Sample: HepG2 (human) cell Lysate at 40 μg A549 (human) cell Lysate at 40 μg Primary: Anti-CELF3 (TMAB-04217) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 57 kD 3. Sample: Lovo (human) cell Lysate at 40 μg Primary: Anti-CELF3 (TMAB-04217 ) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kD Observed band size: 57 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. |
| Tissue Specificity | Expressed in brain. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010] |
| Immunogen | KLH conjugated synthetic peptide: human CELF3 |
| Antigen Species | Human |
| Gene Name | CELF3 |
| Gene ID | |
| Protein Name | CUGBP Elav-like family member 3 |
| Uniprot ID | |
| Function | RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA. |
| Molecular Weight | Theoretical: 52 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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