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Anti-ELMOD2 Polyclonal Antibody

Catalog No. TMAB-05542 Copy Product Info
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Anti-ELMOD2 Polyclonal Antibody is a Rabbit antibody targeting ELMOD2. Anti-ELMOD2 Polyclonal Antibody can be used in WB.

Anti-ELMOD2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-05542

Anti-ELMOD2 Polyclonal Antibody is a Rabbit antibody targeting ELMOD2. Anti-ELMOD2 Polyclonal Antibody can be used in WB.

Anti-ELMOD2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ELMOD2 Polyclonal Antibody is a Rabbit antibody targeting ELMOD2. Anti-ELMOD2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Cow,Horse,Rabbit)
Verified Activity
Sample: oocyte (Mouse) CellLysate at 40 μg
Primary: Anti-ELMOD2 (TMAB-05542) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 35 kD
Observed band size: 35 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityAlveolar cells (morphologically type II cells) and alveolar macrophages (at protein level). Expressed in brain, colon, heart, kidney, liver, lung, muscle, placenta, small intestine, spleen, stomach and testis. In lung it is expressed in alveolar macrophages and alveolar walls.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundELMOD2 is a 293 amino acid protein that is one of six human proteins that contain an ELMO domain. ELMOD2 is thought to interact with DOCK1 through a SH3-binding site, which enhances the guanine nucleotide exchange factor (GEF) activity of DOCK1. Therefore, ELMOD2 may also be part of a complex with DOCK1 and Rac1 that is required to activate Rac Rho small GTPases. Evidence of decreased ELMOD2 expression in lung of individuals with familial idiopathic pulmonary fibrosis (IPF) suggests that defects in the gene encoding ELMOD2 may be linked to susceptibility for familial IPF.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ELMOD2
Antigen Species
Human
Gene Name
ELMOD2
Gene ID
Protein Name
ELMO domain-containing protein 2
Uniprot ID
Function
Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses.
Chemical Properties
Molecular WeightTheoretical: 35 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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