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Anti-CHRNA2 (neuronal) Polyclonal Antibody
😃Good
Catalog No. TMAB-04328
Anti-CHRNA2 (neuronal) Polyclonal Antibody is a Rabbit antibody targeting CHRNA2 (neuronal). Anti-CHRNA2 (neuronal) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-CHRNA2 (neuronal) Polyclonal Antibody
Anti-CHRNA2 (neuronal) Polyclonal Antibody
😃Good
Catalog No. TMAB-04328
Anti-CHRNA2 (neuronal) Polyclonal Antibody is a Rabbit antibody targeting CHRNA2 (neuronal). Anti-CHRNA2 (neuronal) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CHRNA2 (neuronal) Polyclonal Antibody is a Rabbit antibody targeting CHRNA2 (neuronal). Anti-CHRNA2 (neuronal) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Dog,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence. [provided by RefSeq]. |
| Immunogen | KLH conjugated synthetic peptide: human CHRNA2 |
| Antigen Species | Human |
| Gene Name | CHRNA2 |
| Gene ID | |
| Protein Name | Neuronal acetylcholine receptor subunit alpha-2 |
| Uniprot ID | |
| Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
| Molecular Weight | Theoretical: 57 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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