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Anti-Bak Polyclonal Antibody

Catalog No. TMAB-03020 Copy Product Info
🥰Excellent
Anti-Bak Polyclonal Antibody is a Rabbit antibody targeting Bak. Anti-Bak Polyclonal Antibody can be used in WB.

Anti-Bak Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-03020

Anti-Bak Polyclonal Antibody is a Rabbit antibody targeting Bak. Anti-Bak Polyclonal Antibody can be used in WB.

Anti-Bak Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Bak Polyclonal Antibody is a Rabbit antibody targeting Bak. Anti-Bak Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Verified Activity
Sample:
Lane 1: Molt-4 (Human) Cell Lysate at 30 μg
Lane 2: Jurkat (Human) Cell Lysate at 30 μg
Primary: Anti-Bak (TMAB-03020) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 23 kD
Observed band size: 25 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion membrane.
Tissue SpecificityExpressed in a wide variety of tissues.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Bak
Antigen Species
Human
Gene Name
BAK1
Gene ID
Protein Name
Bcl-2 homologous antagonist/killer
Uniprot ID
Function
In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.
Chemical Properties
Molecular WeightTheoretical: 23 kDa. Actual: 25 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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