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Anti-ADAMTS10 Polyclonal Antibody
😃Good
Catalog No. TMAB-02299
Anti-ADAMTS10 Polyclonal Antibody is a Rabbit antibody targeting ADAMTS10. Anti-ADAMTS10 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-ADAMTS10 Polyclonal Antibody
Anti-ADAMTS10 Polyclonal Antibody
😃Good
Catalog No. TMAB-02299
Anti-ADAMTS10 Polyclonal Antibody is a Rabbit antibody targeting ADAMTS10. Anti-ADAMTS10 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-ADAMTS10 Polyclonal Antibody is a Rabbit antibody targeting ADAMTS10. Anti-ADAMTS10 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Pig,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Widely expressed in adult tissues. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | ADAMTS10 is a member of the ADAMs family of proteinases with Thrombospondin motifs. The catalytic site of ADAMTS10 is typical of the metalloproteinase catalytic domains, with an HExxHxxxxxH sequence, perhaps giving these enzymes some shared specificity. ADAMTS10 is closest in homology to ADAMTS6, sharing 53% overall identity. Functional mutations in ADAMTS10 have been linked to Weill Marchesani syndrome, a connective tissue disorder marked by fibrillin 1 misprocessing. ADAMTS10 has also been reported to be over expressed in breast cancer tissues and cell lines. |
| Immunogen | KLH conjugated synthetic peptide: human ADAMTS10 |
| Antigen Species | Human |
| Gene Name | ADAMTS10 |
| Gene ID | |
| Protein Name | A disintegrin and metalloproteinase with thrombospondin motifs 10 |
| Uniprot ID | |
| Function | Metalloprotease that participate in microfibrils assembly. Microfibrils are extracellular matrix components occurring independently or along with elastin in the formation of elastic tissues. |
| Molecular Weight | Theoretical: 95 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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