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Anti-DCD Monoclonal Antibody (Synonyms: Preproteolysin, Dermcidin)
Catalog No. TMAZ-0265 Copy Product Info
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Anti-DCD Monoclonal Antibody is a humanized rabbit antibody targeting DCD. Anti-DCD Monoclonal Antibody can be used in ELISA,FCM.
Anti-DCD Monoclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAZ-0265
Synonyms Preproteolysin, Dermcidin
Anti-DCD Monoclonal Antibody is a humanized rabbit antibody targeting DCD. Anti-DCD Monoclonal Antibody can be used in ELISA,FCM.
Anti-DCD Monoclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μg | $196 | 12 days | 12 days | |
| 50 μg | $236 | 12 days | 12 days | |
| 100 μg | $330 | 12 days | 12 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-DCD Monoclonal Antibody is a humanized rabbit antibody targeting DCD. Anti-DCD Monoclonal Antibody can be used in ELISA,FCM. |
| Synonyms | Preproteolysin, Dermcidin |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of DCD overexpressed 472F cells with TMAZ-0265, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Single-pass type I membrane |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of DCD protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Found in sweat, has an antimicrobial activity during early bacterial colonization (PubMed: 11694882, PubMed: 23426625). The secreted peptide assembles into homohexameric complexes that can associate with and also insert into pathogen membranes (PubMed: 23426625). Once inserted in bacteria membranes forms anion channels probably altering the transmembrane potential essential for bacterial survival (PubMed: 23426625). Highly effective against E.coli, E.faecalis, S.aureus and C.albicans (PubMed: 11694882). Optimal pH and salt concentration resemble the conditions in sweat (PubMed: 11694882). Also exhibits proteolytic activity, cleaving on the C-terminal side of Arg and, to a lesser extent, Lys residues (PubMed: 17448443)|Promotes survival of neurons and displays phosphatase activity (PubMed: 9736629). It may bind IgG (PubMed: 9736629) |
| Conjucates | Unconjugated |
| Others Formats | Biotin |
| Antibody Types Available | 2 |
| Immunogen | DCD |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Other Functions |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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