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Anti-Caspase-7 p11 Polyclonal Antibody
Catalog No. TMAB-03667 Copy Product Info
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Anti-Caspase-7 p11 Polyclonal Antibody is a Rabbit antibody targeting Caspase-7 p11. Anti-Caspase-7 p11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Caspase-7 p11 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-03667
Anti-Caspase-7 p11 Polyclonal Antibody is a Rabbit antibody targeting Caspase-7 p11. Anti-Caspase-7 p11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Caspase-7 p11 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-Caspase-7 p11 Polyclonal Antibody is a Rabbit antibody targeting Caspase-7 p11. Anti-Caspase-7 p11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| Verified Activity | Images provided the Independent Validation Program (badge number 029653) Formalin-fixed and paraffin embedded human prostate labeled with Rabbit Anti-Caspase-7 Polyclonal Antibody (TMAB-03667) at 1: 250 overnight at room temperature followed by conjugation to secondary antibody. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq]. |
| Immunogen | KLH conjugated synthetic peptide: human caspase-7 isoform alpha subunit p11 |
| Antigen Species | Human |
| Gene Name | CASP7 |
| Gene ID | |
| Protein Name | Caspase-7 |
| Uniprot ID | |
| Function | Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death. |
| Molecular Weight | Theoretical: 11/33 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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