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Anti-LULL1/TOR1AIP2 Polyclonal Antibody
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Catalog No. TMAB-08449
Anti-LULL1/TOR1AIP2 Polyclonal Antibody is a Rabbit antibody targeting LULL1/TOR1AIP2. Anti-LULL1/TOR1AIP2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-LULL1/TOR1AIP2 Polyclonal Antibody
Anti-LULL1/TOR1AIP2 Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-08449
Anti-LULL1/TOR1AIP2 Polyclonal Antibody is a Rabbit antibody targeting LULL1/TOR1AIP2. Anti-LULL1/TOR1AIP2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-LULL1/TOR1AIP2 Polyclonal Antibody is a Rabbit antibody targeting LULL1/TOR1AIP2. Anti-LULL1/TOR1AIP2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (LULL1) Polyclonal Antibody, Unconjugated (TMAB-08449) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded (mouse kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (LULL1) Polyclonal Antibody, Unconjugated (TMAB-08449) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 3. Sample: Lane 1: K562 (Human) Cell Lysate at 30 μg Lane 2: SH-SY5Y (Human) Cell Lysate at 30 μg Lane 3: Hela (Human) Cell Lysate at 30 μg Lane 4: HUVEC (Human) Cell Lysate at 30 μg Lane 5: U2os (Human) Cell Lysate at 30 μg Lane 6: HepG2 (Human) Cell Lysate at 30 μg Lane 7: Liver (Mouse) Lysate at 40 μg Lane 8: Liver (Rat) Lysate at 40 μg Lane 9: Kidney (Mouse) Lysate at 40 μg Lane 10: Cerebrum (Mouse) Lysate at 40 μg Lane 11: Cerebrum (Rat) Lysate at 40 μg Primary: Anti-LULL1/TOR1AIP2 (TMAB-08449) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51 kD Observed band size: 51 kD 4. Sample: Placenta (Mouse) Lysate at 40 μg Large intestine (Mouse) Lysate at 40 μg Primary: Anti-LULL1/TOR1AIP2 (TMAB-08449) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51 kD Observed band size: 56 kD 5. Sample: Small intestine (Mouse) Lysate at 40 μg Primary: Anti-LULL1/TOR1AIP2 (TMAB-08449) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51 kD Observed band size: 56 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | LULL1 is a 470 amino acid endoplasmic reticulum single-pass membrane protein belonging to the TOR1AIP family. LULL1 interacts with torsinA, an essential AAA+ ATPase found in the endoplasmic reticulum (ER) and nuclear envelope (NE) of higher eukaryotes. LULL1 regulates the distribution and activity of torsinA within the ER and NE lumen and reveals functional defects in mutant torsinA, which is responsible for DYT1 dystonia, a neurodevelopmental disease caused by an in-frame deletion (Deltagag) in the gene encoding torsinA. The gene encoding LULL1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. |
| Immunogen | KLH conjugated synthetic peptide: human LULL1 |
| Antigen Species | Human |
| Gene Name | TOR1AIP2 |
| Gene ID | |
| Protein Name | Torsin-1A-interacting protein 2 |
| Uniprot ID | |
| Function | Regulates the distribution of TOR1A between the endoplasmic reticulum and the nuclear envelope. |
| Molecular Weight | Theoretical: 51 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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