Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-Phospho-PDPK1 (Tyr373+Tyr376) Polyclonal Antibody
Copy Product Info
🥰Excellent
Synonyms:
Catalog No. TMAB-11130 Copy Product Info
🥰Excellent
Anti-Phospho-PDPK1 (Tyr373+Tyr376) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PDPK1 (Tyr373+Tyr376). Anti-Phospho-PDPK1 (Tyr373+Tyr376) Polyclonal Antibody can be used in WB.
Anti-Phospho-PDPK1
(Tyr373+Tyr376) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $221 | 7-10 days | 7-10 days | |
| 100 µL | $373 | 7-10 days | 7-10 days | |
| 200 µL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Phospho-PDPK1 (Tyr373+Tyr376) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PDPK1 (Tyr373+Tyr376). Anti-Phospho-PDPK1 (Tyr373+Tyr376) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow) |
| Verified Activity | Sample: Liver (Mouse) Lysate at 40 μg Heart (Mouse) Lysate at 40 μg Primary: Anti-Phospho-PDPK1 (Tyr373+Tyr376) (TMAB-11130) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 61 kD Observed band size: 61 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation. Tyrosine phosphorylation seems to occur only at the plasma membrane. |
| Tissue Specificity | Appears to be expressed ubiquitously. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human PDPK1 around the phosphorylation site of (Y373+Y376) |
| Antigen Species | Human |
| Gene Name | PDPK1 |
| Gene ID | |
| Protein Name | 3-phosphoinositide-dependent protein kinase 1 |
| Uniprot ID | |
| Function | Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive. |
| Molecular Weight | Theoretical: 61 kDa. Actual: 61 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: Anti-Phospho-PDPK1 (Tyr373+Tyr376) Polyclonal Antibody molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.