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Antibacterial agent 125

Name: Antibacterial agent 125
Brand: TargetMol
SKU: T72047
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T72047Cas No. 1274611-43-6

Antibacterial Agent 125 exhibits potent antimicrobial activity against clinically relevant Gram-positive pathogens, displaying Minimum Inhibitory Concentration (MIC) 50 values ranging from 0.25 to 8 μM. It is suitable for researching antimicrobial resistance.

Antibacterial agent 125

🥰Excellent

Purity: 98.45%

Catalog No. T72047Cas No. 1274611-43-6

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$39	-	In Stock
10 mg	$64	-	In Stock
25 mg	$128	-	In Stock
50 mg	$213	-	In Stock
100 mg	$328	-	In Stock
500 mg	$788	-	In Stock
1 mL x 10 mM (in DMSO)	$43	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.45%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Antibacterial Agent 125 exhibits potent antimicrobial activity against clinically relevant Gram-positive pathogens, displaying Minimum Inhibitory Concentration (MIC) 50 values ranging from 0.25 to 8 μM. It is suitable for researching antimicrobial resistance.
Targets&IC50	Gram-positive pathogens:0.25-8 Μm(MIC50)
In vitro	Antibacterial agent 125 exhibits potent inhibition against methicillin-resistant Staphylococcus aureus strains while displaying no cytotoxic effects in human cells.[1] Antibacterial agent 125 does not promote resistance even after ten passages and demonstrates a moderate capacity to hinder biofilm formation.[1]

Chemical Properties

Molecular Weight	270.71
Formula	C₁₅H₁₁ClN₂O
Cas No.	1274611-43-6
Smiles	N(C(CC1=CC(Cl)=CC=C1)=O)C2=CC=C(C#N)C=C2
Relative Density.	1.29 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 225.0 mg/mL (831.1 mM), Sonication and heating to 60℃ are recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 5 mg/mL (18.47 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6940 mL	18.4699 mL	36.9399 mL	184.6995 mL
5 mM	0.7388 mL	3.6940 mL	7.3880 mL	36.9399 mL
10 mM	0.3694 mL	1.8470 mL	3.6940 mL	18.4699 mL
20 mM	0.1847 mL	0.9235 mL	1.8470 mL	9.2350 mL
50 mM	0.0739 mL	0.3694 mL	0.7388 mL	3.6940 mL
100 mM	0.0369 mL	0.1847 mL	0.3694 mL	1.8470 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc