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Anti-GASC1/KDM4C Polyclonal Antibody
Catalog No. TMAB-06345 Copy Product Info
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Anti-GASC1/KDM4C Polyclonal Antibody is a Rabbit antibody targeting GASC1/KDM4C. Anti-GASC1/KDM4C Polyclonal Antibody can be used in WB.
Anti-GASC1/KDM4C Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-06345
Anti-GASC1/KDM4C Polyclonal Antibody is a Rabbit antibody targeting GASC1/KDM4C. Anti-GASC1/KDM4C Polyclonal Antibody can be used in WB.
Anti-GASC1/KDM4C Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GASC1/KDM4C Polyclonal Antibody is a Rabbit antibody targeting GASC1/KDM4C. Anti-GASC1/KDM4C Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit) |
| Verified Activity | Sample: A431 (Human) Cell Lysate at 30 μg HepG2 (Human) Cell Lysate at 30 μg Hela (Human) Cell Lysate at 30 μg HL60 (Human) Cell Lysate at 30 μg Primary: Anti-GASC1/KDM4C (TMAB-06345) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 100/120 kD Observed band size: 120 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Overexpressed in several esophageal squamous cell carcinomas (ESCs). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | KDM4C/JMJD2C, a jumonji domain containing protein, is a histone demethylase. JMJD2C specifically demethylates Lysine 9 and Lysine 36 residues of Histone H3, thereby playing a central role in regulating histone modifications. |
| Immunogen | KLH conjugated synthetic peptide: human GASC1/KDM4C |
| Antigen Species | Human |
| Gene Name | KDM4C |
| Gene ID | |
| Protein Name | Lysine-specific demethylase 4C |
| Uniprot ID | |
| Function | Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. |
| Molecular Weight | Theoretical: 120 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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