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Anti-RANK Polyclonal Antibody 2
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Catalog No. TMAB-12080
Anti-RANK Polyclonal Antibody 2 is a Rabbit antibody targeting RANK. Anti-RANK Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Anti-RANK Polyclonal Antibody 2
Anti-RANK Polyclonal Antibody 2
😃Good
Catalog No. TMAB-12080
Anti-RANK Polyclonal Antibody 2 is a Rabbit antibody targeting RANK. Anti-RANK Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-RANK Polyclonal Antibody 2 is a Rabbit antibody targeting RANK. Anti-RANK Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. |
| Tissue Specificity | Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012] |
| Immunogen | Recombinant Protein: human RANK protein |
| Antigen Species | Human |
| Gene Name | TNFRSF11A |
| Gene ID | |
| Protein Name | Tumor necrosis factor receptor superfamily member 11A |
| Uniprot ID | |
| Function | Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. |
| Molecular Weight | Theoretical: 66 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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