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Anti-NET1 Polyclonal Antibody 3

Catalog No. TMAB-09363 Copy Product Info
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Anti-NET1 Polyclonal Antibody 3 is a Rabbit antibody targeting NET1. Anti-NET1 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.

Anti-NET1 Polyclonal Antibody 3

Copy Product Info
🥰Excellent
Catalog No. TMAB-09363

Anti-NET1 Polyclonal Antibody 3 is a Rabbit antibody targeting NET1. Anti-NET1 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.

Anti-NET1 Polyclonal Antibody 3
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-NET1 Polyclonal Antibody 3 is a Rabbit antibody targeting NET1. Anti-NET1 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (NET1) Polyclonal Antibody, Unconjugated (TMAB-09363) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm (By similarity). Nucleus
Tissue SpecificityWidely expressed.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene is part of the family of Rho guanine nucleotide exchange factors. Members of this family activate Rho proteins by catalyzing the exchange of GDP for GTP. The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation. Pseudogenes of this gene are located on the long arms of chromosomes 1, 7 and 18. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NET1
Antigen Species
Human
Gene Name
NET1
Gene ID
Protein Name
Neuroepithelial cell-transforming gene 1 protein
Uniprot ID
Function
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
Chemical Properties
Molecular WeightTheoretical: 68 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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