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Anti-PTPN13 Polyclonal Antibody

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Catalog No. TMAB-11926

Anti-PTPN13 Polyclonal Antibody is a Rabbit antibody targeting PTPN13. Anti-PTPN13 Polyclonal Antibody can be used in FCM.

Anti-PTPN13 Polyclonal Antibody

Anti-PTPN13 Polyclonal Antibody

😃Good
Catalog No. TMAB-11926
Anti-PTPN13 Polyclonal Antibody is a Rabbit antibody targeting PTPN13. Anti-PTPN13 Polyclonal Antibody can be used in FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PTPN13 Polyclonal Antibody is a Rabbit antibody targeting PTPN13. Anti-PTPN13 Polyclonal Antibody can be used in FCM.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit)
Application
Recommended Dose
FCM: 3μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm, cytoskeleton. Nucleus. Cell projection, lamellipodium.
Tissue SpecificityPresent in most tissues with the exception of the liver and skeletal muscle. Most abundant in lung, kidney and fetal brain.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundPTPN13 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as I-kappa-B-alpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FAP1/PTPN13
Antigen Species
Human
Gene Name
PTPN13
Gene ID
Protein Name
Tyrosine-protein phosphatase non-receptor type 13
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 273 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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