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Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody
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Catalog No. TMAB-10308
Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody is a Rabbit antibody targeting Phospho-alpha Adducin (Ser436). Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody can be used in WB.
Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody
Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody
😃Good
Catalog No. TMAB-10308
Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody is a Rabbit antibody targeting Phospho-alpha Adducin (Ser436). Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody is a Rabbit antibody targeting Phospho-alpha Adducin (Ser436). Anti-Phospho-alpha Adducin (Ser436) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Chicken,Dog,Cow,Horse) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side. |
| Tissue Specificity | Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Adducins are a family of cytoskeleton proteins encoded by three genes (Alpha, Beta, Gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical actin network organization. Adducin Alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin Alpha and Adducin Gamma is ubiquitous in contrast to the restricted expression of Adducin Beta. Adducin Beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow, in humans, and in spleen in mice. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human alpha Adducin around the phosphorylation site of Ser436 |
| Antigen Species | Human |
| Gene Name | ADD1 |
| Gene ID | |
| Protein Name | alpha-adducin |
| Uniprot ID | |
| Function | Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. |
| Molecular Weight | Theoretical: 81 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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