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Anti-NUP50 Polyclonal Antibody

Catalog No. TMAB-09707 Copy Product Info
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Anti-NUP50 Polyclonal Antibody is a Rabbit antibody targeting NUP50. Anti-NUP50 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-NUP50 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-09707

Anti-NUP50 Polyclonal Antibody is a Rabbit antibody targeting NUP50. Anti-NUP50 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-NUP50 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-NUP50 Polyclonal Antibody is a Rabbit antibody targeting NUP50. Anti-NUP50 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Dog,Pig,Horse,Rabbit)
Verified Activity
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min;
Incubation: Anti-NUP50 Polyclonal Antibody, Unconjugated (TMAB-09707) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side (By similarity). Note=Localizes to the nucleoplasmic fibrils of the nuclear pore complex (By similarity).
Tissue SpecificityUbiquitous. Highest levels in testis, peripheral blood leukocytes and fetal liver.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNUP50 is a component of the nuclear pore complex that has a direct role in nuclear protein export. NUP50 may serve as a binding site on the nuclear side of the pore complex for export receptor-cargo complexes. NUP50 interacts with multiple transport receptor proteins including p27Kip1. This interaction is required for correct intracellular transport and degradation of p27Kip1.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NUP50
Antigen Species
Human
Gene Name
NUP50
Gene ID
Protein Name
Nuclear pore complex protein Nup50
Uniprot ID
Function
Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
Chemical Properties
Molecular WeightTheoretical: 50 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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