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Anti-IL-23R Polyclonal Antibody
Catalog No. TMAB-07642 Copy Product Info
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Anti-IL-23R Polyclonal Antibody is a Rabbit antibody targeting IL-23R. Anti-IL-23R Polyclonal Antibody can be used in WB,ELISA.
Anti-IL-23R Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-07642
Anti-IL-23R Polyclonal Antibody is a Rabbit antibody targeting IL-23R. Anti-IL-23R Polyclonal Antibody can be used in WB,ELISA.
Anti-IL-23R Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-IL-23R Polyclonal Antibody is a Rabbit antibody targeting IL-23R. Anti-IL-23R Polyclonal Antibody can be used in WB,ELISA. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Sample: Lane 1: Lymph node (Mouse) Lysate at 40 μg Lane 2: Lymph node (Rat) Lysate at 40 μg Lane 3: Thymus (Rat) Lysate at 40 μg Primary: Anti-IL-23R (TMAB-07642) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 67 kD Observed band size: 75 kD 2. Sample: Lane 1: Human K562 cell lysates Lane 2: Human Jurkat cell lysates Primary: Anti-IL-23R (TMAB-07642) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 67 kDa Observed band size: 68 kDa |
| Application | |
| Recommended Dose | WB: 1:500-1000; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. |
| Immunogen | KLH conjugated synthetic peptide: human IL-23R |
| Antigen Species | Human |
| Gene Name | IL23R |
| Gene ID | |
| Protein Name | Interleukin-23 receptor |
| Uniprot ID | |
| Function | Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. |
| Molecular Weight | Theoretical: 67 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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