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Anti-SERPINB1 Polyclonal Antibody
Catalog No. TMAB-12682 Copy Product Info
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Anti-SERPINB1 Polyclonal Antibody is a Rabbit antibody targeting SERPINB1. Anti-SERPINB1 Polyclonal Antibody can be used in WB.
Anti-SERPINB1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-12682
Anti-SERPINB1 Polyclonal Antibody is a Rabbit antibody targeting SERPINB1. Anti-SERPINB1 Polyclonal Antibody can be used in WB.
Anti-SERPINB1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-SERPINB1 Polyclonal Antibody is a Rabbit antibody targeting SERPINB1. Anti-SERPINB1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat) |
| Verified Activity | 1. Sample: U937 (Human) Cell Lysate at 30 μg Primary: Anti-SERPINB1 (TMAB-12682) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kD Observed band size: 40 kD 2. Sample: U937 (Human) Cell Lysate at 30 μg Primary: Anti-SERPINB1 (TMAB-12682) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 43 kD Observed band size: 43 kD 3. Sample: Heart (Mouse) Lysate at 40 μg Uterus (Mouse) Lysate at 40 μg Primary: Anti-EDNRa at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 47 kD Observed band size: 47 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Construction | Polyclonal Antibody |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. The monocyte/neutrophil elastase inhibitor gene, SERPINB1, belongs to the Ov-serpin family (ovalbumin-related serpins). Human SerpinB1, also designated monocyte/neutrophil elastase inhibitor (M/NEI) or leukocyte elastase inhibitor (LEI), is a cytoplasmic protein which acts as a fast-acting stoichiometric proteinase inhibitor that regulates the activity of neutrophil elastase (NE), cathepsin-G and proteinase-3. There are four homologous genes in mouse designated SerpinB1a, SerpinB1b, SerpinB1c and the pseudogene, Serpinb1-ps1. The three protein-coding genes share significant sequence identity, however SerpinB1a (also designated EIA) has been characterized as the functional ortholog of human SerpinB1. |
| Immunogen | KLH conjugated synthetic peptide: human SERPINB1 |
| Antigen Species | Human |
| Gene Name | SERPINB1 |
| Gene ID | |
| Protein Name | Leukocyte elastase inhibitor |
| Uniprot ID | |
| Function | Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. |
| Molecular Weight | Theoretical: 43 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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