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Anti-MAD3 Polyclonal Antibody
Catalog No. TMAB-08500 Copy Product Info
🥰Excellent
Anti-MAD3 Polyclonal Antibody is a Rabbit antibody targeting MAD3. Anti-MAD3 Polyclonal Antibody can be used in WB.
Anti-MAD3 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-08500
Anti-MAD3 Polyclonal Antibody is a Rabbit antibody targeting MAD3. Anti-MAD3 Polyclonal Antibody can be used in WB.
Anti-MAD3 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-MAD3 Polyclonal Antibody is a Rabbit antibody targeting MAD3. Anti-MAD3 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig,Cat) |
| Verified Activity | Sample: MCF-7 (Mouse) Cell Lysate at 30 μg Primary: Anti-MAD3 (TMAB-08500) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 23 kD Observed band size: 42 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008] |
| Immunogen | KLH conjugated synthetic peptide: human MAD3 |
| Antigen Species | Human |
| Gene Name | MXD3 |
| Gene ID | |
| Protein Name | Max dimerization protein 3 |
| Uniprot ID | |
| Function | Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation. |
| Molecular Weight | Theoretical: 23 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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