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Anti-ELAC2/HPC2 Polyclonal Antibody

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Catalog No. TMAB-05529

Anti-ELAC2/HPC2 Polyclonal Antibody is a Rabbit antibody targeting ELAC2/HPC2. Anti-ELAC2/HPC2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-ELAC2/HPC2 Polyclonal Antibody

Anti-ELAC2/HPC2 Polyclonal Antibody

😃Good
Catalog No. TMAB-05529
Anti-ELAC2/HPC2 Polyclonal Antibody is a Rabbit antibody targeting ELAC2/HPC2. Anti-ELAC2/HPC2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ELAC2/HPC2 Polyclonal Antibody is a Rabbit antibody targeting ELAC2/HPC2. Anti-ELAC2/HPC2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Rabbit)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion. Nucleus. Note=Mainly mitochondrial.
Tissue SpecificityWidely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundELAC2 is a zinc phosphodiesterase which displays some tRNA 3' processing endonuclease activity. It is thought to be involved in tRNA maturation, acting by removing a 3' trailer from precursor tRNA. ELAC2 also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. A number of allelic variants have been investigated in hereditary prostate cancer.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ELAC2
Antigen Species
Human
Gene Name
ELAC2
Gene ID
60528
Protein Name
Zinc phosphodiesterase ELAC protein 2
Uniprot ID
Q9BQ52
Function
Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
Chemical Properties
Molecular WeightTheoretical: 92 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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