Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-ABCD3 Polyclonal Antibody is a Rabbit antibody targeting ABCD3. Anti-ABCD3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-ABCD3 Polyclonal Antibody is a Rabbit antibody targeting ABCD3. Anti-ABCD3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Synonyms | ZWS2, PXMP1, PXMP 1, PMP70, PMP 70, Peroxisomal membrane protein 1, ATP-binding cassette sub-family D member 3, ATP binding cassette sub family D(ALD) member 3, ATP binding cassette sub family D member 3, ABCD3_HUMAN, ABCD3 protein, ABCD 3, ABC43, ABC D3, ABC 43, 70 kDa peroxisomal membrane protein |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat) |
| Verified Activity | Tissue/cell: human cervical carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min; Incubation: Anti-PXMP1/ABCD3/PMP70 Polyclonal Antibody, Unconjugated (TMAB-02153) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Peroxisome membrane; Multi-pass membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The peroxisomal membrane contains several ATP-binding cassette (ABC) transporters, ABCD1-4 that are known to be present in the human peroxisome membrane. All four proteins are ABC half-transporters, which dimerize to form an active transporter. A mutation in the ABCD1 gene causes X-linked adreno-leukodystrophy (X-ALD), a peroxisomal disorder which affects lipid storage. ABCD2 in mouse is expressed at high levels in the brain and adrenal organs, which are adversely affected in X-ALD. The peroxisomal membrane comprises two quantitatively major proteins, PMP22 and ABCD3. ABCD3 is associated with irregularly shaped vesicles which may be defective peroxisomes or peroxisome precursors. ABCD1 localizes to peroxisomes. ABCB7 is a half-transporter involved in the transport of heme from the mitochondria to the cytosol. |
| Immunogen | KLH conjugated synthetic peptide: human PXMP1/ABCD3 |
| Antigen Species | Human |
| Gene Name | ABCD3 |
| Gene ID | |
| Protein Name | ATP-binding cassette sub-family D member 3 |
| Uniprot ID | |
| Function | Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity. |
| Molecular Weight | Theoretical: 75 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
|---|

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.