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Anti-SPHK2 Polyclonal Antibody 2
Catalog No. TMAB-13111 Copy Product Info
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Anti-SPHK2 Polyclonal Antibody 2 is a Rabbit antibody targeting SPHK2. Anti-SPHK2 Polyclonal Antibody 2 can be used in ICC/IF.
Anti-SPHK2 Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAB-13111
Anti-SPHK2 Polyclonal Antibody 2 is a Rabbit antibody targeting SPHK2. Anti-SPHK2 Polyclonal Antibody 2 can be used in ICC/IF.
Anti-SPHK2 Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-SPHK2 Polyclonal Antibody 2 is a Rabbit antibody targeting SPHK2. Anti-SPHK2 Polyclonal Antibody 2 can be used in ICC/IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat) |
| Verified Activity | SH-SY5Y cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Antibody incubation with (SPHK2) polyclonal Antibody, Unconjugated 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue) was used to stain the cell nuclei. |
| Application | |
| Recommended Dose | ICC/IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1: Cytoplasm. Membrane. Isoform 2: Lysosome membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a kinase that phosphorylates sphingosine into sphingosine-1-phosphate, which is involved in cell differentiation, motility, and apoptosis. The encoded protein plays a role in maintaining cellular levels of sphingosine-1-phosphate. The gene product also enhances apoptosis in different cell types and suppresses cellular proliferation. In mast cells, the encoded protein is necessary for influx of calcium, protein kinase C activation, and cytokine production and degranulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq]. |
| Immunogen | KLH conjugated synthetic peptide: human SPHK2 |
| Antigen Species | Human |
| Gene Name | SPHK2 |
| Gene ID | |
| Protein Name | Sphingosine kinase 2 |
| Uniprot ID | |
| Function | Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides. |
| Molecular Weight | Theoretical: 72 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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