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Anti-alpha Lactalbumin Polyclonal Antibody
Catalog No. TMAB-02472 Copy Product Info
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Anti-alpha Lactalbumin Polyclonal Antibody is a Rabbit antibody targeting alpha Lactalbumin. Anti-alpha Lactalbumin Polyclonal Antibody can be used in WB.
Anti-alpha Lactalbumin Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-02472
Anti-alpha Lactalbumin Polyclonal Antibody is a Rabbit antibody targeting alpha Lactalbumin. Anti-alpha Lactalbumin Polyclonal Antibody can be used in WB.
Anti-alpha Lactalbumin Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-alpha Lactalbumin Polyclonal Antibody is a Rabbit antibody targeting alpha Lactalbumin. Anti-alpha Lactalbumin Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | Sample: Lane1: Human milk Lysates Lane2: Human milk Lysates Primary: Anti-alpha Lactalbumin (TMAB-02472) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 14 kD Observed band size: 14 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Mammary gland specific. Secreted in milk. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Alpha-lactalbumin is the B protein of lactose synthetase secreted by the mammary epithelial cells. It is a potent Ca2+-elevating and apoptosis-inducing agent with broad, yet selective, cytotoxic activity. Multimeric ?lactalbumin has been shown to kill all transformed, embryonic and lymphoid cells tested, but not mature epithelial elements. This suggests that milk contributes to mucosal immunity not only by furnishing antimicrobial molecules but also by policing the function of lymphocytes and epithelium. ?lactalbumin may be helpful in discovering the site of origin of metastatic breast tumors. Human lactalbumin contains 123 amino acid residues. Comparison of the 5' flanking sequences of the two Alpha-lactalbumin genes with those of five casein genes reveals the presence of a highly conserved region extending from position -140 to -110 in all seven sequences examined, suggesting a possible regulatory role in the hormonal control or tissue-specific expression of milk protein genes in the mammary gland. |
| Immunogen | KLH conjugated synthetic peptide: human LALBA/alpha Lactalbumin |
| Antigen Species | Human |
| Gene Name | LALBA |
| Gene ID | |
| Protein Name | alpha-lactalbumin |
| Uniprot ID | |
| Function | Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins. |
| Molecular Weight | Theoretical: 14 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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