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Anti-IL11 Monoclonal Antibody

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Catalog No. TMAZ-0001
Alias Interleukin-11, Adipogenesis inhibitory factor

Anti-IL11 Monoclonal Antibody is a humanized rabbit antibody targeting IL11. Anti-IL11 Monoclonal Antibody can be used in ELISA,FCM.

Anti-IL11 Monoclonal Antibody

Anti-IL11 Monoclonal Antibody

😃Good
Catalog No. TMAZ-0001Alias Interleukin-11, Adipogenesis inhibitory factor
Anti-IL11 Monoclonal Antibody is a humanized rabbit antibody targeting IL11. Anti-IL11 Monoclonal Antibody can be used in ELISA,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μg$19612 days12 days
50 μg$23612 days12 days
100 μg$33012 days12 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity
Description
Anti-IL11 Monoclonal Antibody is a humanized rabbit antibody targeting IL11. Anti-IL11 Monoclonal Antibody can be used in ELISA,FCM.
SynonymsInterleukin-11, Adipogenesis inhibitory factor
Ig Type
Rabbit monoclonal IgG
Reactivity
Human
Verified Activity
Flow cytometry analysis of IL11 overexpressed 437F cells with TMAZ-0001, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
Application
ELISA
FCM
Recommended Dose
0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationGPI-anchor
ConstructionThis antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IL11 protein.
PurificationProtein A Affinity Purified
AppearanceLiquid
Formulation0.22 μm filtered solution in PBS.
Purity> 95% as determined by SDS-PAGE.
Research BackgroundCytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed: 2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and IL11RA activates a signaling cascade that promotes cell proliferation (PubMed: 12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling' (PubMed: 30279168)
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Biotin
Antibody Types Available
2
Antigen Details
Immunogen
IL11
Antigen Species
Human
Gene ID
3589
Uniprot ID
P20809
Biology Area
Immunology Research
Chemical Properties
Molecular Weight150 kDa
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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