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Anti-PFKFB3/PFK2 Polyclonal Antibody

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Catalog No. TMAB-10223

Anti-PFKFB3/PFK2 Polyclonal Antibody is a Rabbit antibody targeting PFKFB3/PFK2. Anti-PFKFB3/PFK2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-PFKFB3/PFK2 Polyclonal Antibody

Anti-PFKFB3/PFK2 Polyclonal Antibody

😃Good
Catalog No. TMAB-10223
Anti-PFKFB3/PFK2 Polyclonal Antibody is a Rabbit antibody targeting PFKFB3/PFK2. Anti-PFKFB3/PFK2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PFKFB3/PFK2 Polyclonal Antibody is a Rabbit antibody targeting PFKFB3/PFK2. Anti-PFKFB3/PFK2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityUbiquitous.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PFKFB3
Antigen Species
Human
Gene Name
PFKFB3
Gene ID
Protein Name
6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3
Uniprot ID
Function
Synthesis and degradation of fructose 2,6-bisphosphate.
Chemical Properties
Molecular WeightTheoretical: 59 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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