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Anti-TNFRSF1B Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting TNFRSF1B. Anti-TNFRSF1B Monoclonal Antibody-Biotin can be used in ELISA,FCM,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μg | $120 | 12 days | 12 days | |
| 50 μg | $143 | 12 days | 12 days | |
| 100 μg | $201 | 12 days | 12 days |
| Description | Anti-TNFRSF1B Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting TNFRSF1B. Anti-TNFRSF1B Monoclonal Antibody-Biotin can be used in ELISA,FCM,IF. |
| Synonyms | Tumor necrosis factor receptor type II, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, p80 TNF-alpha receptor, p75 |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of TNFRSF1B overexpressed 293F cells with TMAZ-0045BBI, which was counjucated with SA-PE (red). The WT 293F control is black line. |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Single-pass type I membrane |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of TNFRSF1B protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity |
| Conjucates | Biotin |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | TNFRSF1B |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology Research |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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