Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Thrombomodulin Polyclonal Antibody

😃Good
Catalog No. TMAB-13521

Anti-Thrombomodulin Polyclonal Antibody is a Rabbit antibody targeting Thrombomodulin. Anti-Thrombomodulin Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-Thrombomodulin Polyclonal Antibody

Anti-Thrombomodulin Polyclonal Antibody

😃Good
Catalog No. TMAB-13521
Anti-Thrombomodulin Polyclonal Antibody is a Rabbit antibody targeting Thrombomodulin. Anti-Thrombomodulin Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5297-10 days7-10 days
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Product Introduction

Bioactivity
Description
Anti-Thrombomodulin Polyclonal Antibody is a Rabbit antibody targeting Thrombomodulin. Anti-Thrombomodulin Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Dog,Cow)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
Tissue SpecificityEndothelial cells are unique in synthesizing thrombomodulin.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThrombomodulin, TM is cell surface glycoprotein; plays an important role in the protein C anticoagulant pathway. It located in a vein, artery and capillary endothelial cells on the surface of plasma membrane protein. It is generally believed: TM vascular endothelial injury is an important parameter is the thrombin receptor, known in a variety of normal human tissues, can also be expressed in many tumors, TM may be similar to the E-cadherin,and is a lectin Like activity of a new class of members of the cell adhesion molecules. CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII; thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse Thrombomodulin
Antigen Species
Mouse
Gene Name
THBD
Gene ID
Protein Name
Thrombomodulin
Uniprot ID
Function
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
Chemical Properties
Molecular WeightTheoretical: 61 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-Thrombomodulin Polyclonal Antibody | purchase Anti-Thrombomodulin Polyclonal Antibody | Anti-Thrombomodulin Polyclonal Antibody cost | order Anti-Thrombomodulin Polyclonal Antibody | Anti-Thrombomodulin Polyclonal Antibody molecular weight