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Anti-Nova2 Polyclonal Antibody
😃Good
Catalog No. TMAB-09575
Anti-Nova2 Polyclonal Antibody is a Rabbit antibody targeting Nova2. Anti-Nova2 Polyclonal Antibody can be used in FCM.
Anti-Nova2 Polyclonal Antibody
Anti-Nova2 Polyclonal Antibody
😃Good
Catalog No. TMAB-09575
Anti-Nova2 Polyclonal Antibody is a Rabbit antibody targeting Nova2. Anti-Nova2 Polyclonal Antibody can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Nova2 Polyclonal Antibody is a Rabbit antibody targeting Nova2. Anti-Nova2 Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Chicken,Dog,Rabbit) |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Brain. Expression restricted to astrocytes. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Nova-1 and Nova-2 are members of a superfamily of protein regulators of RNA metabolism in neurons. Both are nuclear RNA binding proteins with K homology motifs, conserved protein sequences which bind to RNA (1,2). Nova proteins, normally sequestered in the central nervous system, are expressed by systemic tumors in patients with the autoimmune disorder paraneoplastic opsoclonus-myoclonus ataxia (POMA) (3,4). Nova-1 is expressed in the hindbrain and ventral spinal cord and Nova-2 is expressed in the neocortex and hippocampus (4). Nova-1 is necessary for regulating neuron-specific alternative splicing of the glycine receptor Alpha2 pre-mRNA (5). |
| Immunogen | KLH conjugated synthetic peptide: human Nova2 |
| Antigen Species | Human |
| Gene Name | NOVA2 |
| Gene ID | |
| Protein Name | RNA-binding protein Nova-2 |
| Uniprot ID | |
| Function | NOVA2 may regulate RNA splicing or metabolism in a specific subset of developing neurons. It binds single strand RNA. |
| Molecular Weight | Theoretical: 49 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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