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Anti-EphB2 Polyclonal Antibody 2
😃Good
Catalog No. TMAB-05621
Anti-EphB2 Polyclonal Antibody 2 is a Rabbit antibody targeting EphB2. Anti-EphB2 Polyclonal Antibody 2 can be used in WB,FCM.
Anti-EphB2 Polyclonal Antibody 2
Anti-EphB2 Polyclonal Antibody 2
😃Good
Catalog No. TMAB-05621
Anti-EphB2 Polyclonal Antibody 2 is a Rabbit antibody targeting EphB2. Anti-EphB2 Polyclonal Antibody 2 can be used in WB,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-EphB2 Polyclonal Antibody 2 is a Rabbit antibody targeting EphB2. Anti-EphB2 Polyclonal Antibody 2 can be used in WB,FCM. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog,Cow) |
| Application | |
| Recommended Dose | WB: 1:500-2000; FCM: 3μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite. |
| Tissue Specificity | Brain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. Preferentially expressed in fetal brain. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015] |
| Immunogen | KLH conjugated synthetic peptide: human EPHB2 |
| Antigen Species | Human |
| Gene Name | EPHB2 |
| Gene ID | |
| Protein Name | Ephrin type-B receptor 2 |
| Uniprot ID | |
| Function | Receptor for members of the ephrin-B family. Phosphorylates ARHGEF15, leading to its ubiquitination and degradation by the proteasome which promotes EFNB1-dependent synapse formation. Can function in aspects of retinal ganglion cell axon guidance to the optic disk even when lacking its tyrosine kinase domain. Acts as a tumor suppressor. |
| Molecular Weight | Theoretical: 108 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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