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Anti-ZGPAT Polyclonal Antibody
Catalog No. TMAB-14314 Copy Product Info
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Anti-ZGPAT Polyclonal Antibody is a Rabbit antibody targeting ZGPAT. Anti-ZGPAT Polyclonal Antibody can be used in WB.
Anti-ZGPAT Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-14314
Anti-ZGPAT Polyclonal Antibody is a Rabbit antibody targeting ZGPAT. Anti-ZGPAT Polyclonal Antibody can be used in WB.
Anti-ZGPAT Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ZGPAT Polyclonal Antibody is a Rabbit antibody targeting ZGPAT. Anti-ZGPAT Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Rabbit) |
| Verified Activity | Sample: HepG2 (Human) Cell Lysate at 30 μg Liver (Mouse) Lysate at 40 μg Primary: Anti-ZGPAT (TMAB-14314) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57 kD Observed band size: 57 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Widely expressed. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | ZGPAT is a 531 amino acid protein that contains a G-patch domain, which is typically found within RNA-binding proteins. Proteins that contain the G-patch domain include some tumor suppressor and DNA-damage repair proteins. ZGPAT also contains one C3H1-type zinc finger, which further supports its probable role as an RNA-binding protein. The gene encoding ZGPAT is inactivated via differential methylation in a oligodendroglioma cell line, suggesting that ZGPAT may have utility as a biomarker. There are two isoforms of ZGPAT that are produced as a result of alternative splicing events. |
| Immunogen | KLH conjugated synthetic peptide: human ZGPAT |
| Antigen Species | Human |
| Gene Name | ZGPAT |
| Gene ID | |
| Protein Name | Zinc finger CCCH-type with G patch domain-containing protein |
| Uniprot ID | |
| Function | Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. |
| Molecular Weight | Theoretical: 57 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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