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Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA is a bioactive peptide acting as a selective agonist for the protease-activated receptor 1 (PAR-1), demonstrating higher specificity for PAR-1 compared to PAR-2. PAR-1, part of the G protein-coupled receptor subfamily, is known to mediate cellular functions of thrombin. Beyond thrombin's various cellular roles, PAR-1 has been shown to interact with PAR-4, influencing thrombin-induced hepatocellular carcinoma, which forms thrombin in the tumor environment and is classified as "coagulation type."
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 TFA is a bioactive peptide acting as a selective agonist for the protease-activated receptor 1 (PAR-1), demonstrating higher specificity for PAR-1 compared to PAR-2. PAR-1, part of the G protein-coupled receptor subfamily, is known to mediate cellular functions of thrombin. Beyond thrombin's various cellular roles, PAR-1 has been shown to interact with PAR-4, influencing thrombin-induced hepatocellular carcinoma, which forms thrombin in the tumor environment and is classified as "coagulation type." |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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