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Anti-CYP3A1 Polyclonal Antibody

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Catalog No. TMAB-04894

Anti-CYP3A1 Polyclonal Antibody is a Rabbit antibody targeting CYP3A1. Anti-CYP3A1 Polyclonal Antibody can be used in WB.

Anti-CYP3A1 Polyclonal Antibody

Anti-CYP3A1 Polyclonal Antibody

😃Good
Catalog No. TMAB-04894
Anti-CYP3A1 Polyclonal Antibody is a Rabbit antibody targeting CYP3A1. Anti-CYP3A1 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CYP3A1 Polyclonal Antibody is a Rabbit antibody targeting CYP3A1. Anti-CYP3A1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Rat
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum, membrane bound.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCYP3A proteins are P450 monooxygenases and in animals, P450 enzymes serve two major functions: biosynthesis of steroids, fatty acids and bile acids, and the metabolism of endogenous and exogenous substrates. A wide variety of exogenous substrates are metabolized by P450 enzymes, including toxins and drugs. The four major families involved in drug metabolism are CYP1, 2, 3 and 4. The hepatic CYP3A1 protein is detected throughout ciliated and nonciliated cells in seven-day-old rats, and is only detected in the apex of these cells in adult rats. Rat CYP3A1 and CYP3A2 share 89% homolgy, but differ by three out of five of their C-terminal residues.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: rat CYP3A1
Antigen Species
Rat
Gene Name
Cyp3a1
Gene ID
Protein Name
Cytochrome P450 3A1
Uniprot ID
Function
In animals, P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs. The four major families involved in drug metabolism are CYP 1,2,3, and 4. Cytochrome P450 3A4 [human-3A1 Rat] is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.
Chemical Properties
Molecular WeightTheoretical: 57 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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