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Anti-CYP3A1 Polyclonal Antibody
Catalog No. TMAB-04894 Copy Product Info
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Anti-CYP3A1 Polyclonal Antibody is a Rabbit antibody targeting CYP3A1. Anti-CYP3A1 Polyclonal Antibody can be used in WB.
Anti-CYP3A1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-04894
Anti-CYP3A1 Polyclonal Antibody is a Rabbit antibody targeting CYP3A1. Anti-CYP3A1 Polyclonal Antibody can be used in WB.
Anti-CYP3A1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CYP3A1 Polyclonal Antibody is a Rabbit antibody targeting CYP3A1. Anti-CYP3A1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Rat |
| Verified Activity | Sample: Liver (Rat) Lysate at 40 μg Cerebrum (Rat) Lysate at 40 μg Primary: Anti-CYP3A1 (TMAB-04894) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57 kD Observed band size: 57 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum, membrane bound. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | CYP3A proteins are P450 monooxygenases and in animals, P450 enzymes serve two major functions: biosynthesis of steroids, fatty acids and bile acids, and the metabolism of endogenous and exogenous substrates. A wide variety of exogenous substrates are metabolized by P450 enzymes, including toxins and drugs. The four major families involved in drug metabolism are CYP1, 2, 3 and 4. The hepatic CYP3A1 protein is detected throughout ciliated and nonciliated cells in seven-day-old rats, and is only detected in the apex of these cells in adult rats. Rat CYP3A1 and CYP3A2 share 89% homolgy, but differ by three out of five of their C-terminal residues. |
| Immunogen | KLH conjugated synthetic peptide: rat CYP3A1 |
| Antigen Species | Rat |
| Gene Name | Cyp3a1 |
| Gene ID | |
| Protein Name | Cytochrome P450 3A1 |
| Uniprot ID | |
| Function | In animals, P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs. The four major families involved in drug metabolism are CYP 1,2,3, and 4. Cytochrome P450 3A4 [human-3A1 Rat] is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin. |
| Molecular Weight | Theoretical: 57 kDa. Actual: 57 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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