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Anti-Phospho-ACACA (Ser79) Polyclonal Antibody 2

Catalog No. TMAB-10283 Copy Product Info
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Anti-Phospho-ACACA (Ser79) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-ACACA (Ser79). Anti-Phospho-ACACA (Ser79) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.

Anti-Phospho-ACACA (Ser79) Polyclonal Antibody 2

Copy Product Info
🥰Excellent
Catalog No. TMAB-10283

Anti-Phospho-ACACA (Ser79) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-ACACA (Ser79). Anti-Phospho-ACACA (Ser79) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.

Anti-Phospho-ACACA
(Ser79) Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-ACACA (Ser79) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-ACACA (Ser79). Anti-Phospho-ACACA (Ser79) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Sheep,GuineaPig)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (P-ACACA (Ser79)) Polyclonal Antibody, Unconjugated (TMAB-10283) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
Tissue SpecificityExpressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundAcetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated synthesised phosphopeptide: mouse Acetyl Coenzyme A Carboxylase around the phosphorylation site of Ser79
Antigen Species
Mouse
Gene Name
ACACA
Gene ID
Protein Name
Acetyl-CoA carboxylase 1
Uniprot ID
Function
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
Chemical Properties
Molecular WeightTheoretical: 266 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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