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Anti-IL11 Monoclonal Antibody-Biotin (Synonyms: Interleukin-11, Adipogenesis inhibitory factor)
Catalog No. TMAZ-0001B Copy Product Info
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Anti-IL11 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting IL11. Anti-IL11 Monoclonal Antibody-Biotin can be used in ELISA,FCM.
Anti-IL11 Monoclonal Antibody-Biotin
Copy Product Info🥰Excellent
Catalog No. TMAZ-0001B
Synonyms Interleukin-11, Adipogenesis inhibitory factor
Anti-IL11 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting IL11. Anti-IL11 Monoclonal Antibody-Biotin can be used in ELISA,FCM.
Anti-IL11 Monoclonal Antibody-Biotin
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μg | $196 | 12 days | 12 days | |
| 50 μg | $236 | 12 days | 12 days | |
| 100 μg | $330 | 12 days | 12 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-IL11 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting IL11. Anti-IL11 Monoclonal Antibody-Biotin can be used in ELISA,FCM. |
| Synonyms | Interleukin-11, Adipogenesis inhibitory factor |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of IL11 overexpressed 437F cells with TMAZ-0001B, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | GPI-anchor |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IL11 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed: 2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and IL11RA activates a signaling cascade that promotes cell proliferation (PubMed: 12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling' (PubMed: 30279168) |
| Conjucates | Biotin |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | IL11 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology Research |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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