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Anti-FBXL18 Polyclonal Antibody

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Catalog No. TMAB-05921

Anti-FBXL18 Polyclonal Antibody is a Rabbit antibody targeting FBXL18. Anti-FBXL18 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,WB.

Anti-FBXL18 Polyclonal Antibody

Anti-FBXL18 Polyclonal Antibody

😃Good
Catalog No. TMAB-05921
Anti-FBXL18 Polyclonal Antibody is a Rabbit antibody targeting FBXL18. Anti-FBXL18 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-FBXL18 Polyclonal Antibody is a Rabbit antibody targeting FBXL18. Anti-FBXL18 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Cow,Horse,Rabbit,Sheep)
Application
IHC-P
IHC-Fr
ICC/IF
IF
WB
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundFBL18 (F-box and leucine-rich repeat protein 18), also known as FBXL18, is an 805 amino acid protein that contains an F-box near its N-terminus, followed by several leucine-rich repeats and a transmembrane domain at the C-terminus. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins and cyclin-dependent kinase inhibitors (CDKNs), for degradation by the proteasome after ubiquitination. FBL18 directly interacts with SKP1A p19 and CUL-1, forming a substrate-recognition component of the SCF-type E3 ubiquitin ligase complex. Four isoforms of FBL18 exist due to alternative splicing.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FBXL18
Antigen Species
Human
Gene Name
FBXL18
Gene ID
80028
Protein Name
F-box/LRR-repeat protein 18
Uniprot ID
Q96ME1
Function
FBXL18 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Chemical Properties
Molecular WeightTheoretical: 88 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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