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Anti-FBXL18 Polyclonal Antibody
Catalog No. TMAB-05921 Copy Product Info
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Anti-FBXL18 Polyclonal Antibody is a Rabbit antibody targeting FBXL18. Anti-FBXL18 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,WB.
Anti-FBXL18 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-05921
Anti-FBXL18 Polyclonal Antibody is a Rabbit antibody targeting FBXL18. Anti-FBXL18 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,WB.
Anti-FBXL18 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-FBXL18 Polyclonal Antibody is a Rabbit antibody targeting FBXL18. Anti-FBXL18 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | 30 μg total protein per lane of various lysates (see on figure) probed with FBXL18 polyclonal antibody, unconjugated (TMAB-05921) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | FBL18 (F-box and leucine-rich repeat protein 18), also known as FBXL18, is an 805 amino acid protein that contains an F-box near its N-terminus, followed by several leucine-rich repeats and a transmembrane domain at the C-terminus. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins and cyclin-dependent kinase inhibitors (CDKNs), for degradation by the proteasome after ubiquitination. FBL18 directly interacts with SKP1A p19 and CUL-1, forming a substrate-recognition component of the SCF-type E3 ubiquitin ligase complex. Four isoforms of FBL18 exist due to alternative splicing. |
| Immunogen | KLH conjugated synthetic peptide: human FBXL18 |
| Antigen Species | Human |
| Gene Name | FBXL18 |
| Gene ID | |
| Protein Name | F-box/LRR-repeat protein 18 |
| Uniprot ID | |
| Function | FBXL18 is a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. |
| Molecular Weight | Theoretical: 88 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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