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Anti-VGLL2 Polyclonal Antibody

Catalog No. TMAB-14093 Copy Product Info
🥰Excellent
Anti-VGLL2 Polyclonal Antibody is a Rabbit antibody targeting VGLL2. Anti-VGLL2 Polyclonal Antibody can be used in WB.

Anti-VGLL2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-14093

Anti-VGLL2 Polyclonal Antibody is a Rabbit antibody targeting VGLL2. Anti-VGLL2 Polyclonal Antibody can be used in WB.

Anti-VGLL2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-VGLL2 Polyclonal Antibody is a Rabbit antibody targeting VGLL2. Anti-VGLL2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit)
Verified Activity
Sample: Muscle (Mouse) Lysate at 40 μg
Primary: Anti-VGLL2 (TMAB-14093) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 33 kD
Observed band size: 35 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificitySkeletal muscle.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundVgl-2, also known as VITO-1, is a 317 amino acid protein that contains a domain through which it interacts with TEF-1, a protein that plays a role in controlling the expression of numerous genes. Specific to skeletal muscle, Vgl-2 is expressed highly in adult fast muscle and is expressed at lower levels in adult slow muscle and fetal skeletal muscle. During muscle differentiation, Vgl-2 mRNA levels increase and Vgl-2 translocates from the cytoplasm to the nucleus. Overexpression of Vgl-2 in MYOD-transfected 10T1/2 mouse embryonic fibroblasts increases expression of myosin heavy chain (MHC), which is a marker of terminal muscle differentiation. This evidence suggests that Vgl-2 is essential for muscle gene expression. There are two isoforms of Vgl-2 that are produced as a result of alternative splicing events.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human VGLL2
Antigen Species
Human
Gene Name
VGLL2
Gene ID
Protein Name
Transcription cofactor vestigial-like protein 2
Uniprot ID
Function
May act as a specific coactivator for the mammalian TEFs. May play a role in the development of skeletal muscles.
Chemical Properties
Molecular WeightTheoretical: 33 kDa. Actual: 35 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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