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Anti-PCDH12 Polyclonal Antibody

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Catalog No. TMAB-10046

Anti-PCDH12 Polyclonal Antibody is a Rabbit antibody targeting PCDH12. Anti-PCDH12 Polyclonal Antibody can be used in WB,FCM.

Anti-PCDH12 Polyclonal Antibody

Anti-PCDH12 Polyclonal Antibody

😃Good
Catalog No. TMAB-10046
Anti-PCDH12 Polyclonal Antibody is a Rabbit antibody targeting PCDH12. Anti-PCDH12 Polyclonal Antibody can be used in WB,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PCDH12 Polyclonal Antibody is a Rabbit antibody targeting PCDH12. Anti-PCDH12 Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Cow,Horse,Sheep)
Application
WB
FCM
Recommended Dose
WB: 1:500-2000; FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane. Cell junction.
Tissue SpecificityExpressed in highly vascularized tissues including the heart and placenta, but most tissues contain a low level of expression. Prominent expression in the spleen.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PCDH12
Antigen Species
Human
Gene Name
PCDH12
Gene ID
51294
Protein Name
Protocadherin-12
Uniprot ID
Q9NPG4
Function
Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions. Promotes homotypic calcium dependent aggregation and adhesion and clusters at intercellular junctions. Unable to bind to catenins, weakly associates with the cytoskeleton.
Chemical Properties
Molecular WeightTheoretical: 126 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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