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Anti-GRF2 Polyclonal Antibody

Catalog No. TMAB-06766 Copy Product Info
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Anti-GRF2 Polyclonal Antibody is a Rabbit antibody targeting GRF2. Anti-GRF2 Polyclonal Antibody can be used in WB.

Anti-GRF2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-06766

Anti-GRF2 Polyclonal Antibody is a Rabbit antibody targeting GRF2. Anti-GRF2 Polyclonal Antibody can be used in WB.

Anti-GRF2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GRF2 Polyclonal Antibody is a Rabbit antibody targeting GRF2. Anti-GRF2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Cow,Sheep)
Verified Activity
1. Sample: Placenta (Mouse) Lysate at 40 μg
Primary: Anti-GRF2 (TMAB-06766) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 140 kD
Observed band size: 120 kD
2. Sample:
Lane 1: Human MCF-7 cell lysates
Lane 2: Human HL-60 cell lysates
Lane 3: Human JAR cell lysates
Lane 4: Human HeLa cell lysates
Primary: Anti-GRF2 (TMAB-06766) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 140 kDa
Observed band size: 140 kDa
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityUbiquitously expressed in adult and fetus. Expression is high in adult skeletal muscle and placenta and in fetal brain and heart. Low levels of expression in adult and fetal liver.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human GRF2
Antigen Species
Human
Gene Name
RAPGEF1
Gene ID
Protein Name
Rap guanine nucleotide exchange factor 1
Uniprot ID
Function
Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS.
Chemical Properties
Molecular WeightTheoretical: 140 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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